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Structure of 866620-21-5
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5-(tert-Butyl)pyridin-2-amine features a sterically hindered tert-butyl group that enhances solubility and stability in organic media. The pyridine nitrogen and primary amine facilitate coordination in catalytic systems, while the para-positioned amine enables selective functionalization. This compound serves as a robust ligand scaffold for transition metal complexes.
5-(tert-Butyl)pyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its pyridine scaffold offers strong coordination capacity and tunable basicity, while the tert-butyl group enhances steric shielding and metabolic stability. The amine functionality facilitates direct derivatization, and the compound exhibits excellent bench stability and ease of purification—ideal for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: