Fmoc-Gly-Val-OH

Name: Fmoc-Gly-Val-OH
Brand: ChemScene
Availability: InStock
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CAS No. 86895-14-9
Cat. No. CS-W014467
Purity≥98%
MDL No.MFCD00190884

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 86895-14-9

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Description

Fmoc-Gly-Val-OH is a protected dipeptide building block designed for solid-phase peptide synthesis. The Fmoc group enables orthogonal protection of the α-amino function, while the valine side chain remains unmodified. This derivative offers high stability under standard bench conditions and integrates seamlessly into iterative coupling protocols, streamlining the assembly of complex peptide sequences.

Application

Fmoc-Gly-Val-OH serves as a key building block in solid-phase peptide synthesis, enabling efficient sequential coupling of amino acids. The Fmoc group provides orthogonal protection for the α-amino function, allowing selective deprotection under mild basic conditions. Its glycine-valine sequence offers high solubility and reduced aggregation during synthesis, while the valine side chain supports diverse downstream modifications. This dipeptide is bench-stable, easily purified by recrystallization or chromatography, and widely used in the construction of therapeutic peptides and bioactive scaffolds.

General Information

CAS No. 86895-14-9
Cat. No. CS-W014467
Purity ≥98%
MDL No. MFCD00190884
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₂H₂₄N₂O₅
Molecular Weight 396.44
Synonym(s) N-Fmoc-glycyl-L-valine
SMILES O=C([C@H](C(C)C)NC(CNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)=O)O

Computational Chemistry Data

TPSA 104.73
LogP 2.7505
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 7

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS07,GHS09
Signal Word : Danger	UN#: 3077
Class : 9	Packing Group : Ⅲ
Hazard Statements : H302+H312-H315-H318-H411
Precautionary Statements : P264-P270-P273-P280-P302+P352-P330-P362+P364-P391-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Fmoc

Life Science Amino Acids and their Derivatives Valine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

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Fmoc-Gly-Val-OH

CAS No. 86895-14-9

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