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Structure of 869725-53-1
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This boronate moiety integrates a trifluoromethyl group and a bromo substituent on a phenyl ring, delivering enhanced electron-withdrawing character and improved stability under standard conditions. The methanol functionality enables direct coupling or oxidation to carboxylic acid derivatives in synthetic sequences.
(2-Bromo-5-(trifluoromethyl)phenyl)methanol serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo and benzyl alcohol functionalities. The trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the benzylic alcohol allows for derivatization via oxidation or protection. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient synthesis of complex arylated scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: