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CS-W001157 4
Total: USD 88.00

2-(2-Chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

  • CAS No. 870195-94-1

  • Cat. No. CS-W000990
  • Purity≥97%
  • MDL No.MFCD05663846

*For research and further manufacturing use only, not for direct human use.

2-(2-Chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-W000990

Structure of 870195-94-1

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General Information

  • CAS No. 870195-94-1
  • Cat. No. CS-W000990
  • Purity ≥97%
  • MDL No. MFCD05663846
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆BClO₂
  • Molecular Weight 238.52
  • Synonym(s) 2-Chlorophenylboronic Acid, Pinacol Ester
  • SMILES Clc1ccccc1B1OC(C(O1)(C)C)(C)C

Description

This boronate ester features a 2-chlorophenyl group conjugated to a tetramethyl-1,3,2-dioxaborolane ring, enabling efficient Suzuki-Miyaura coupling under standard conditions. The electron-deficient aryl chloride integrates readily into complex molecular architectures, while the stable dioxaborolane moiety ensures excellent shelf life and moisture tolerance during handling.

Synthesis

  • Route1
    • In-stock
      2,3-Dimethylbutane-2,3-diol|CS-0015356
      76-09-5
    • null|null
      22092-92-8
    • null|null
      1956-97-4
    • ~57%
    • In-stock
      2-(2-Chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-W000990
      870195-94-1

    References

    • UNIVERSITE DE BORDEAUX 1; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; PUCHEAULT, Mathieu Jonathan Damien; MARCIASINI, Ludovic Daniel Alain; VAULTIER, Michel Patent: WO2014/9169 A1, 2014 ; Location in patent: Page/Page column 53-54; 67-68 ;
  • Route2
    • null|null
      108-90-7
    • In-stock
      Bis(pinacolato)diborane|CS-D1216
      73183-34-3
    • ~49%
    • In-stock
      2-(2-Chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-W000990
      870195-94-1

    References

    • Kawamorita, Soichiro; Ohmiya, Hirohisa; Hara, Kenji; Fukuoka, Atsushi; Sawamura, Masaya Journal of the American Chemical Society, 2009 , vol. 131, p. 5058 - 5059
  • Route3

    References

    • Sumida, Yuto; Kato, Tomoe; Hosoya, Takamitsu Organic Letters, 2013 , vol. 15, # 11 p. 2806 - 2809

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H413
Precautionary Statements : P264-P270-P273-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   2.6392
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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