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Structure of 870483-68-4
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This trifluoromethyl-substituted naphthyridine dihydrochloride features a rigid, electron-deficient heterocyclic core with enhanced solubility and stability under standard conditions. The dihydrochloride salt form improves handling and crystallinity, enabling straightforward integration into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine dihydrochloride serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. The trifluoromethyl group enhances metabolic stability and membrane permeability, while the dihydrochloride salt form ensures excellent solubility and bench stability. It functions effectively in standard amine coupling reactions and facilitates downstream functionalization for drug discovery applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: