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CS-W001157 4
Total: USD 88.00

6-Azaspiro[2.5]octane

  • CAS No. 872-64-0

  • Cat. No. CS-0047202
  • Purity≥98%
  • MDL No.MFCD14581272

*For research and further manufacturing use only, not for direct human use.

6-Azaspiro[2.5]octane|CS-0047202

Structure of 872-64-0

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General Information

  • CAS No. 872-64-0
  • Cat. No. CS-0047202
  • Purity ≥98%
  • MDL No. MFCD14581272
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃N
  • Molecular Weight 111.18
  • Synonym(s) None
  • SMILES C12(CC2)CCNCC1

Description

6-Azaspiro[2.5]octane features a rigid, bridged bicyclic core with a nitrogen atom at the 6-position, conferring enhanced solubility and metabolic stability. This scaffold integrates readily into medicinal chemistry libraries, offering a well-defined three-dimensional architecture ideal for probing target selectivity in drug discovery.

Application

6-Azaspiro[2.5]octane serves as a rigid, bicyclic scaffold enabling precise spatial positioning of functional groups in medicinal chemistry campaigns. Its stable spirocyclic core exhibits excellent bench stability and tolerates a range of reaction conditions, facilitating diverse derivatization via standard amine alkylation or acylation protocols. Functions as a key building block for heterocyclic APIs and bioactive molecule synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.15
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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