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Structure of 872366-63-7
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3-Fluoro-2-nitrobenzaldehyde features a fluorinated benzene ring bearing both nitro and aldehyde functionalities in ortho relationship, enabling selective reactivity in cross-coupling and condensation reactions. This electron-deficient aromatic aldehyde integrates readily into complex molecular architectures under mild conditions.
3-Fluoro-2-nitrobenzaldehyde serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient access to substituted benzimidazoles, quinolines, and other nitrogen-containing scaffolds. Its ortho-nitro and fluoro substituents provide complementary reactivity for sequential functionalization, while the aldehyde group facilitates imine formation and Ugi-type reactions. The compound exhibits good bench stability and is readily purified by recrystallization or flash chromatography, making it well-suited for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P261-P280-P304+P340
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Lot numbers can be found on the outside label of a product: