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Structure of 874959-74-7
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This boronate ester features a sterically hindered tetramethyl-1,3,2-dioxaborolane core paired with a 5-methylthiophen-3-yl group, delivering enhanced stability and reactivity in cross-coupling processes. The electron-rich thiophene moiety facilitates efficient palladium-catalyzed transformations under mild conditions.
4,4,5,5-Tetramethyl-2-(5-methylthiophen-3-yl)-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetramethyl-substituted dioxaborolane enhances air and moisture stability while maintaining high reactivity in palladium-catalyzed transformations. It facilitates efficient coupling with aryl and heteroaryl halides, enabling rapid construction of biaryl and thiophene-containing scaffolds common in pharmaceutical and materials chemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: