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Structure of 87617-23-0
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4-Methyl-2-(trifluoromethyl)aniline features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the methyl substituent provides steric bulk. This combination enables selective reactivity in cross-coupling and electrophilic substitution reactions under standard conditions. The molecule exhibits improved solubility in organic solvents and is bench-stable for routine handling in synthetic workflows.
4-Methyl-2-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds and functionalized aryl derivatives. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the methyl substituent provides a handle for further derivatization. The compound exhibits good bench stability and compatibility with standard coupling reactions, facilitating efficient synthesis of complex intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332
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Precautionary Statements : P262-P280-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: