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Structure of 876601-43-3
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(2-Cyano-4-fluorophenyl)boronic acid features a dual functional handle: a boronic acid group enabling reliable Suzuki-Miyaura coupling and a para-fluorine substituent that enhances electrophilicity for selective cross-coupling. The cyano group imparts electron-withdrawing character, improving stability and reactivity under standard conditions. This combination enables efficient integration into complex heterocycles and pharmaceutical scaffolds.
(2-Cyano-4-fluorophenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The cyano and fluorine substituents provide orthogonal functionalization potential and enhance metabolic stability in medicinal chemistry applications. Its bench-stable nature and compatibility with diverse reaction partners facilitate straightforward purification and scalability.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: