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Structure of 87789-51-3
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2-Chloro-5-fluoro-4-(methylthio)pyrimidine is a fluorinated pyrimidine derivative featuring a methylthio group at the 4-position and halogen substituents at the 2- and 5-positions. This electron-deficient scaffold enables direct coupling in cross-coupling reactions, serving as a key building block for medicinal chemistry applications. The molecule exhibits enhanced stability under standard conditions and facilitates efficient functionalization in late-stage derivatization workflows.
2-Chloro-5-fluoro-4-(methylthio)pyrimidine serves as a versatile building block in heterocyclic synthesis, enabling efficient construction of pyrimidine-based scaffolds. Its orthogonal reactivity—where the chloro and fluoro groups facilitate selective nucleophilic substitution—supports diverse functionalization under mild conditions. The methylthio group enhances solubility and stability, while the overall structure exhibits excellent bench stability and compatibility with standard coupling protocols. This compound functions effectively in the synthesis of pharmaceutical intermediates and agrochemicals.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: