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Structure of 878194-91-3
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3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isonicotinonitrile features a boronate ester group paired with a nitrile-substituted pyridine core. This combination enables efficient Suzuki-Miyaura coupling under mild conditions, delivering aryl nitriles with high functional group tolerance and minimal byproduct formation. The tetramethyl dioxaborolane moiety enhances stability and shelf life, while the para-nitrile position facilitates downstream transformations.
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isonicotinonitrile serves as a versatile boronate building block in palladium-catalyzed cross-coupling reactions. Its nitrile group provides orthogonal functionality for downstream transformations, while the sterically protected boronate moiety ensures excellent stability and compatibility with diverse reaction conditions. Ideal for constructing substituted heterocycles and functionalized aryl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: