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Structure of 878194-93-5
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3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile features a boronate ester group paired with a nitrile-bearing pyridine ring, enabling efficient Suzuki-Miyaura coupling under mild conditions. The tetramethyl-substituted dioxaborolane enhances stability and resistance to protodeboronation. This bifunctional scaffold integrates seamlessly into complex molecular architectures, particularly in pharmaceutical and agrochemical synthesis where traceless functionalization is critical.
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The picolinonitrile moiety provides a readily accessible handle for further functionalization, while the tetramethylboronate group ensures excellent stability, low toxicity, and compatibility with diverse reaction conditions. Its bench-stable nature and high reactivity facilitate efficient synthesis of biaryl and heteroaryl scaffolds in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P233-P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P340-P362-P403-P405-P501
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Lot numbers can be found on the outside label of a product: