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Structure of 878804-93-4
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3-(Difluoromethyl)pyridin-2-amine integrates a difluoromethyl group at the 3-position of a pyridin-2-amine scaffold, delivering enhanced metabolic stability and improved membrane permeability. This electron-deficient heterocycle serves as a key building block in medicinal chemistry, enabling direct incorporation into kinase inhibitors and other bioactive scaffolds through facile functionalization at the amine and pyridine sites.
3-(Difluoromethyl)pyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling direct incorporation of a difluoromethyl group into bioactive scaffolds. Its pyridine nitrogen and primary amine functionality offer orthogonal reactivity for derivatization via coupling, alkylation, or cyclization reactions. The molecule exhibits good bench stability and facilitates efficient functionalization under standard synthetic conditions, making it well-suited for rapid analog generation in drug discovery programs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: