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Structure of 878805-25-5
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3-Cyclopropylpyridin-2-amine features a pyridine core functionalized with a cyclopropyl group at the 3-position and an amine at the 2-position, delivering enhanced electron density and steric profile. This scaffold integrates readily into medicinal chemistry libraries, offering improved metabolic stability and solubility in polar solvents. The strained cyclopropyl ring contributes to unique conformational rigidity, enabling precise spatial orientation in target binding.
3-Cyclopropylpyridin-2-amine serves as a valuable heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds through standard coupling reactions. Its pyridine nitrogen and primary amine functionality offer orthogonal reactivity for C–N bond formation, while the cyclopropyl group enhances metabolic stability and modulates lipophilicity. The compound exhibits good bench stability and compatibility with common reaction conditions, facilitating efficient purification and integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: