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CS-W001157 4
Total: USD 88.00

3-(dimethylamino)-1-phenylpropan-1-one hydrochloride

  • CAS No. 879-72-1

  • Cat. No. CS-0001978
  • Purity≥98%
  • MDL No.MFCD00012481

*For research and further manufacturing use only, not for direct human use.

3-(dimethylamino)-1-phenylpropan-1-one hydrochloride|CS-0001978

Structure of 879-72-1

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General Information

  • CAS No. 879-72-1
  • Cat. No. CS-0001978
  • Purity ≥98%
  • MDL No. MFCD00012481
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆ClNO
  • Molecular Weight 213.70
  • Synonym(s) N,N-dimethyl-3-oxo-3-phenylpropan-1-aminium
  • SMILES O=C(C1=CC=CC=C1)CCN(C)C.Cl

Description

N-Azidoacetylgalactosamine-tetraacylated (Ac4GalNAz) provides the first part of a simple and robust two-step technique that helps identify and characterize cell surface sialic acid-containing glycoproteins. The azide-modified protein can be detected by reaction with alkynes. For example alkynes labeled with a fluorescent probe or a biotin can be used. The acetyl groups increase cell permeability and allow the unnatural sugars to easily pass through the cell membrane. Carboxyesterases remove the acetyl groups once the monosaccharide is in the cell.

Synthesis

  • Route1

    References

    • IND-SWIFT LABORATORIES LIMITED Patent: WO2009/141833 A2, 2009 ; Location in patent: Page/Page column 11 ;
  • Route2
    • null|null
      646-06-0
    • null|null
      506-59-2
    • In-stock
      Acetophenone|CS-0015982
      98-86-2
    • ~89%
    • 3-(dimethylamino)-1-phenylpropan-1-one hydrochloride|CS-0001978
      879-72-1

    References

    • Sumita; Koumori; Ohno Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 8 p. 1676 - 1678
  • Route3
    • In-stock
      4-Chromanone|CS-W007464
      491-37-2
    • null|null
      506-59-2
    • ~55%
    • null|null
      361443-03-0
    • 3-(dimethylamino)-1-phenylpropan-1-one hydrochloride|CS-0001978
      879-72-1

    References

    • Fujiwara, Junya; Sakai, Kazuya; Kibayashi, Kenji; Shimada, Fumiki; Shiga, Yoshio; Takagi, Shiro Patent: US2003/149046 A1, 2003 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.31
  • LogP   2.2428
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   4

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