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Structure of 879088-41-2
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4-Chloro-3-(pyridin-2-yl)aniline features a pyridin-2-yl group conjugated to an electron-deficient aniline scaffold, enabling efficient coupling in transition metal catalysis. The ortho-chloro substituent enhances reactivity in cross-coupling reactions, while the nitrogen-containing heterocycle provides directional coordination for palladium catalysts. This scaffold integrates readily into complex molecular architectures used in pharmaceutical and agrochemical development.
4-Chloro-3-(pyridin-2-yl)aniline serves as a versatile building block in medicinal chemistry, enabling the construction of biologically relevant heterocyclic scaffolds. Its ortho-chloro and aniline functionalities facilitate palladium-catalyzed cross-coupling reactions and direct functionalization, offering high reactivity with minimal side products. The molecule exhibits excellent bench stability and ease of purification, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: