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Structure of 882499-87-8
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Methyl 2-amino-5-bromoisonicotinate features a brominated pyridine core with a strategically positioned amino group, enabling direct functionalization in late-stage derivatization. The methyl ester facilitates subsequent hydrolysis or coupling reactions, while the electron-deficient ring enhances reactivity in cross-coupling processes. This bench-stable compound serves as a key building block for bioactive heterocycles and pharmaceutical intermediates.
Methyl 2-Amino-5-bromoisonicotinate serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the pyridine ring via palladium-catalyzed cross-coupling. The amino and bromo groups provide orthogonal reactivity for sequential modifications, while the methyl ester facilitates downstream derivatization. Its bench-stable crystalline form enables straightforward handling and purification, making it well-suited for scalable synthesis of heterocyclic scaffolds and API intermediates.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: