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Structure of 882672-05-1
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6-Bromo-2-chloroquinazoline is a halogenated quinazoline derivative featuring bromine at the 6-position and chlorine at the 2-position. This electron-deficient scaffold enables direct coupling in cross-coupling reactions, serving as a key building block for pharmaceutical intermediates and functional materials. The molecule exhibits enhanced stability under standard conditions and integrates readily into complex heterocyclic architectures.
6-Bromo-2-chloroquinazoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The bromine at the 6-position facilitates efficient Suzuki, Stille, or Negishi coupling, while the ortho-chloro group offers potential for selective functionalization. Its stability under standard reaction conditions and compatibility with diverse protecting groups make it well-suited for constructing complex quinazoline-based scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: