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Structure of 883107-68-4
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6-Chloro-2-fluoropyridin-3-ol features a trifunctional pyridine core bearing chlorine, fluorine, and hydroxyl groups at strategic positions. This electron-deficient heterocycle serves as a key scaffold in medicinal chemistry, enabling direct coupling reactions under mild conditions. The hydroxyl group enhances solubility and facilitates derivatization, while the adjacent halogen atoms support selective cross-coupling transformations.
6-Chloro-2-fluoropyridin-3-ol serves as a versatile building block in medicinal chemistry, enabling efficient construction of fluorinated heterocyclic scaffolds. Its orthogonal reactivity profile—where the chloro group undergoes palladium-catalyzed coupling and the hydroxyl group participates in derivatization—facilitates rapid diversification. Bench-stable and amenable to standard purification methods, it functions reliably in multi-step syntheses requiring functional group tolerance and predictable regiochemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: