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CS-W001157 4
Total: USD 88.00

2-(5-Bromo-2-fluorophenyl)acetic acid

  • CAS No. 883514-21-4

  • Cat. No. CS-0094802
  • Molecule weight233.03
  • Purity≥97%
  • MDL No.MFCD06246020

*For research and further manufacturing use only, not for direct human use.

2-(5-Bromo-2-fluorophenyl)acetic acid|CS-0094802

Structure of 883514-21-4

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General Information

  • CAS No. 883514-21-4
  • Cat. No. CS-0094802
  • Purity ≥97%
  • MDL No. MFCD06246020
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BrFO₂
  • Molecular Weight 233.03
  • Synonym(s) benzeneacetic acid, 5-bromo-2-fluoro-
  • SMILES O=C(O)CC1=CC(Br)=CC=C1F

Description

2-(5-Bromo-2-fluorophenyl)acetic acid features a brominated and fluorinated aromatic core linked to a carboxylic acid side chain, enabling direct incorporation into pharmaceutical intermediates. The electron-withdrawing halogens enhance reactivity in cross-coupling processes, while the pendant acid group supports derivatization via amide or ester formation. This compound serves as a key building block for bioactive molecule synthesis under standard bench conditions.

Application

2-(5-Bromo-2-fluorophenyl)acetic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-halogenated aryl core enables efficient Pd-catalyzed cross-coupling reactions, while the carboxylic acid functionality supports direct derivatization or incorporation into peptide-like scaffolds. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable medicinal chemistry campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.2153
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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