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Structure of 884494-34-2
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2-Ethynyl-5-fluoropyridine features a conjugated alkyne linked to a fluorinated pyridine ring, enabling efficient coupling in transition-metal-catalyzed reactions. The electron-deficient heterocycle enhances reactivity in cross-coupling processes, while the terminal alkyne facilitates derivatization under mild conditions. This compound serves as a key building block for functionalized aromatic systems in medicinal chemistry and materials science.
2-Ethynyl-5-fluoropyridine serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Sonogashira and Suzuki-Miyaura transformations. The fluorinated pyridine core provides enhanced electronic effects and metabolic stability, while the terminal alkyne functionality offers high reactivity and compatibility with diverse functional groups. This compound exhibits excellent bench stability and facilitates efficient access to complex heterocyclic scaffolds relevant to medicinal chemistry and materials science.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: