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Structure of 884494-51-3
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2-Fluoro-4-iodonicotinic acid is a halogenated pyridine derivative featuring complementary fluorine and iodine substituents at ortho and para positions, respectively. This combination enables selective cross-coupling transformations in medicinal chemistry applications. The carboxylic acid group facilitates direct derivatization and incorporation into bioactive scaffolds. Bench-stable and moisture-tolerant, it streamlines synthetic access to functionalized heterocycles under standard conditions.
2-Fluoro-4-iodonicotinic acid serves as a versatile building block for transition-metal-catalyzed cross-coupling reactions, enabling efficient access to substituted nicotinates. The ortho-fluoro and meta-iodo groups offer complementary reactivity for sequential functionalization, with the carboxylic acid facilitating direct derivatization or salt formation. Bench-stable and compatible with standard purification protocols, it supports scalable synthesis of heterocyclic scaffolds relevant to medicinal chemistry and agrochemical research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: