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Structure of 884495-13-0
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5-Fluoro-4-iodo-2-methoxypyridine features a strategically positioned fluorine atom and iodine handle on a pyridine core, enabling selective cross-coupling transformations. The methoxy group enhances solubility and modulates electronic properties, while the electron-deficient ring facilitates palladium-catalyzed reactions under standard conditions. This bench-stable building block is well-suited for medicinal chemistry and materials synthesis.
5-Fluoro-4-iodo-2-methoxypyridine serves as a versatile building block in cross-coupling chemistry, enabling efficient construction of substituted pyridine scaffolds. The iodine group facilitates reliable Suzuki, Stille, and Negishi couplings, while the fluorine and methoxy groups provide orthogonal reactivity and enhanced stability under standard reaction conditions. This compound is particularly valuable for medicinal chemistry applications requiring regioselective functionalization of heterocyclic cores.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: