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CS-W001157 4
Total: USD 88.00

2-(5-Formylfuran-2-yl)benzoic acid

  • CAS No. 88460-72-4

  • Cat. No. CS-0116819
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(5-Formylfuran-2-yl)benzoic acid|CS-0116819

Structure of 88460-72-4

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General Information

  • CAS No. 88460-72-4
  • Cat. No. CS-0116819
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₈O₄
  • Molecular Weight 216.19
  • Synonym(s) 2-(5-Formyl-furan-2-yl)-benzoic acid
  • SMILES O=C(O)C1=CC=CC=C1C2=CC=C(C=O)O2

Description

2-(5-Formylfuran-2-yl)benzoic acid features a conjugated system linking a formyl-substituted furan ring to a benzoic acid moiety, enabling direct integration into click chemistry and bioconjugation workflows. The aldehyde group facilitates efficient coupling with hydrazides or amines under mild conditions, while the carboxylic acid provides additional anchoring points for derivatization. This bifunctional architecture supports modular synthesis of complex molecular architectures in medicinal chemistry and materials science.

Application

2-(5-Formylfuran-2-yl)benzoic acid serves as a versatile bifunctional building block for medicinal chemistry and materials synthesis, enabling efficient coupling reactions via its carboxylic acid and aldehyde functionalities. The molecule exhibits good bench stability and facilitates straightforward derivatization through reductive amination, condensation, or transition-metal-catalyzed cross-coupling. Its orthogonally reactive groups support modular assembly of complex heterocyclic scaffolds and functionalized aryl systems in standard laboratory workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Computational Chemistry Data

  • TPSA   67.51
  • LogP   2.4573
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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