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Structure of 885518-25-2
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6-Fluoro-1H-indol-4-amine features a fluorinated indole core with a primary amine at the 4-position, enabling direct incorporation into bioactive scaffolds. The electron-withdrawing fluorine substituent enhances metabolic stability and modulates electronic properties for targeted ligand design. This bench-stable derivative serves as a key intermediate in medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.
6-Fluoro-1H-indol-4-amine serves as a versatile building block for the synthesis of bioactive heterocycles, enabling direct incorporation into pharmaceutical scaffolds via standard coupling reactions. Its fluorinated indole core exhibits enhanced metabolic stability and favorable electronic properties, while the primary amine facilitates facile derivatization. The compound demonstrates good bench stability and compatibility with common protecting group strategies, making it well-suited for iterative synthetic approaches in medicinal chemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: