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CS-W001157 4
Total: USD 88.00

6-Bromo-1H-indazol-4-ol

  • CAS No. 885518-77-4

  • Cat. No. CS-W022449
  • Purity≥96%
  • MDL No.MFCD07781339

*For research and further manufacturing use only, not for direct human use.

6-Bromo-1H-indazol-4-ol|CS-W022449

Structure of 885518-77-4

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General Information

  • CAS No. 885518-77-4
  • Cat. No. CS-W022449
  • Purity ≥96%
  • MDL No. MFCD07781339
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrN₂O
  • Molecular Weight 213.03
  • Synonym(s) None
  • SMILES OC1=C2C=NNC2=CC(Br)=C1

Description

6-Bromo-1H-indazol-4-ol features a brominated indazolone core with a phenolic hydroxyl group, offering enhanced reactivity for cross-coupling and functionalization. This bench-stable compound integrates readily into synthetic pathways requiring halogenated heterocycles, enabling efficient access to bioactive scaffolds in medicinal chemistry and materials science.

Application

6-Bromo-1H-indazol-4-ol serves as a versatile building block for the synthesis of biologically active heterocycles, enabling direct functionalization at the C4 position via palladium-catalyzed cross-coupling reactions. Its bromo group facilitates efficient derivatization, while the phenolic hydroxyl supports orthogonal protection strategies and enhances solubility. The compound exhibits excellent bench stability and is readily purified by flash chromatography or recrystallization, making it ideal for iterative medicinal chemistry campaigns and API scaffold elaboration.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   48.91
  • LogP   2.031
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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