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Structure of 882670-69-1
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4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine features a boronate ester group enabling reliable Suzuki-Miyaura coupling under mild conditions. The methyl and amine substituents provide orthogonal reactivity, while the tetramethylcyclopentadienone-derived boronate enhances stability and shelf life. This compound integrates seamlessly into complex molecular architectures with minimal purification needs.
4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. Its ortho-methyl group enhances metabolic stability in bioactive scaffolds, while the pinacol boronate moiety ensures excellent bench stability and compatibility with diverse reaction conditions. The amine functionality enables direct incorporation into pharmaceutical intermediates and functionalized heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: