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CS-W001157 4
Total: USD 88.00

6-Bromo-1H-indazol-4-ol

  • CAS No. 885518-77-4

  • Cat. No. CS-W022449
  • Purity≥96%
  • MDL No.MFCD07781339
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Bromo-1H-indazol-4-ol|CS-W022449

Structure of 885518-77-4

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Description

6-Bromo-1H-indazol-4-ol features a brominated indazolone core with a phenolic hydroxyl group, offering enhanced reactivity for cross-coupling and functionalization. This bench-stable compound integrates readily into synthetic pathways requiring halogenated heterocycles, enabling efficient access to bioactive scaffolds in medicinal chemistry and materials science.

Application

6-Bromo-1H-indazol-4-ol serves as a versatile building block for the synthesis of biologically active heterocycles, enabling direct functionalization at the C4 position via palladium-catalyzed cross-coupling reactions. Its bromo group facilitates efficient derivatization, while the phenolic hydroxyl supports orthogonal protection strategies and enhances solubility. The compound exhibits excellent bench stability and is readily purified by flash chromatography or recrystallization, making it ideal for iterative medicinal chemistry campaigns and API scaffold elaboration.

General Information

  • CAS No. 885518-77-4
  • Cat. No. CS-W022449
  • Purity ≥96%
  • MDL No. MFCD07781339
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrN₂O
  • Molecular Weight 213.03
  • Synonym(s) None
  • SMILES OC1=C2C=NNC2=CC(Br)=C1

Computational Chemistry Data

  • TPSA   48.91
  • LogP   2.031
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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