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Structure of 885519-08-4
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3-Bromo-5-fluoro-1H-indazole is a halogenated heterocyclic scaffold featuring complementary reactive sites for cross-coupling and functionalization. The bromine at the 3-position enables palladium-catalyzed transformations, while the fluorine at the 5-position enhances metabolic stability and modulates electronic properties. This dual functionality supports rapid diversification in medicinal chemistry and materials synthesis.
3-Bromo-5-fluoro-1H-indazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the fluoro substituent enhances metabolic stability and modulates electronic properties. Its bench-stable nature and compatibility with diverse reaction conditions make it a practical choice for constructing complex scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: