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Structure of 885522-46-3
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4-Methoxy-6-methyl-1H-indole is a substituted indole featuring a methoxy group at the 4-position and a methyl group at the 6-position, conferring enhanced electron density and steric bulk. This scaffold serves as a key building block in medicinal chemistry, particularly for bioactive molecules targeting CNS disorders and kinase pathways. The combination of moderate lipophilicity and stability under standard conditions supports its utility in synthetic workflows.
4-Methoxy-6-methyl-1H-indole serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted indole scaffolds via palladium-catalyzed cross-coupling and electrophilic substitution reactions. The methoxy group enhances solubility and modulates electronic properties, while the methyl substituent provides steric control and metabolic stability. Its bench-stable nature and compatibility with diverse reaction conditions facilitate straightforward purification and integration into complex molecular architectures.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: