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Structure of 884494-97-7
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6-Fluoro-2-methylnicotinic acid is a fluorinated nicotinic acid derivative featuring a strategically positioned methyl group and fluorine atom. This combination imparts enhanced metabolic stability and modulates electronic properties, making it valuable for medicinal chemistry applications. The molecule integrates readily into bioactive scaffolds, particularly in kinase inhibitors and CNS-targeted therapeutics. Its bench-stable nature supports straightforward handling under standard conditions.
6-Fluoro-2-methylnicotinic acid serves as a valuable building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-substituted pyridine framework supports diverse functionalization, while the fluorine and methyl groups enhance metabolic stability and modulate electronic properties. The carboxylic acid functionality facilitates coupling reactions, amide formation, and derivatization under standard conditions. Bench-stable and readily purified by recrystallization, it functions effectively in both small-scale research and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: