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CS-W001157 4
Total: USD 88.00

(2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methanol

  • CAS No. 885698-97-5

  • Cat. No. CS-M0481
  • Purity≥97%
  • MDL No.MFCD13190352

*For research and further manufacturing use only, not for direct human use.

(2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methanol|CS-M0481

Structure of 885698-97-5

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General Information

  • CAS No. 885698-97-5
  • Cat. No. CS-M0481
  • Purity ≥97%
  • MDL No. MFCD13190352
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂ClN₃O₂S
  • Molecular Weight 285.75
  • Synonym(s) 2-Chloro-4-(4-Morpholinyl)thieno[3,2-d]pyriMidine-6-Methanol
  • SMILES ClC1=NC2=C(SC(CO)=C2)C(N3CCOCC3)=N1

Synthesis

  • Route1

    References

    • Curis, Inc.; Bao, Rudi; Lai, Chengjung; Qian, Changgeng Patent: US2013/102595 A1, 2013 ; Location in patent: Paragraph 0226; 0227 ;
  • Route2
    • 4-{2-Chlorothieno[3,2-d]pyrimidin-4-yl}morpholine|CS-B0059
      16234-15-4
    • ~91%
    • (2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methanol|CS-M0481
      885698-97-5

    References

    • F. HOFFMANN-LA ROCHE AG Patent: WO2009/53715 A1, 2009 ; Location in patent: Page/Page column 64-65 ; WO 2009/053715 A1
  • Route3
    • null|null
      124773-65-5
    • ~61%
    • (2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methanol|CS-M0481
      885698-97-5

    References

    • Petter, Russell C.; Jewell, Charles F.; Lee, Kwangho; Medikonda, Aravind Prasad; Niu, Deqiang; Qiao, Lixin; Singh, Juswinder; Zhu, Zhendong Patent: US2011/269244 A1, 2011 ; Location in patent: Page/Page column ;

Safety Information

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Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   58.48
  • LogP   1.6736
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   2

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