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Structure of 887267-47-2
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2-Bromo-5-(trifluoromethoxy)aniline features a bromo group at the ortho position and a trifluoromethoxy substituent at the para position relative to the amino group, creating a uniquely electron-deficient aromatic scaffold. This combination enhances reactivity in cross-coupling processes while maintaining bench-stable handling properties under standard conditions.
2-Bromo-5-(trifluoromethoxy)aniline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined halogen reactivity. The trifluoromethoxy group imparts enhanced metabolic stability and lipophilicity, while the aniline functionality allows for facile derivatization. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient synthesis of complex heterocyclic scaffolds and bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: