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Structure of 887578-57-6
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7-Bromo-1H-indazol-3-ol features a brominated indazol scaffold with a phenolic hydroxyl group, enabling direct functionalization in C–H activation and cross-coupling reactions. The electron-deficient heterocycle pairs well with palladium catalysts, while the hydroxyl moiety offers hydrogen-bonding capacity and enhanced solubility in polar solvents. This bench-stable compound serves as a key intermediate for bioactive molecule synthesis.
7-Bromo-1H-indazol-3-ol serves as a versatile building block for medicinal chemistry campaigns, enabling direct functionalization at the C3 position via palladium-catalyzed cross-coupling. Its bromine substituent provides reliable reactivity in Suzuki, Stille, and Negishi reactions, while the phenolic hydroxyl group offers orthogonal handle for derivatization or protection. The compound exhibits good bench stability and facilitates efficient synthesis of indazolyl-containing scaffolds relevant to kinase inhibitor development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: