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CS-W001157 4
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(1R,2S)-1-Amino-1-Phenylpropan-2-ol hydrochloride

  • CAS No. 88784-91-2

  • Cat. No. CS-0745167
  • Molecule weight187.67
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1R,2S)-1-Amino-1-Phenylpropan-2-ol hydrochloride|CS-0745167

Structure of 88784-91-2

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General Information

  • CAS No. 88784-91-2
  • Cat. No. CS-0745167
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₄ClNO
  • Molecular Weight 187.67
  • Synonym(s) None
  • SMILES Cl.C[C@H](O)[C@H](N)C1=CC=CC=C1

Description

This chiral amino alcohol hydrochloride delivers a stereochemically defined scaffold for asymmetric synthesis and medicinal chemistry. The (1R,2S) configuration ensures predictable reactivity in catalytic transformations, while the phenyl group enhances structural rigidity and solubility in polar solvents. Bench-stable under standard conditions, it integrates seamlessly into peptide mimetics and bioactive molecule design.

Application

(1R,2S)-1-Amino-1-phenylpropan-2-ol hydrochloride serves as a chiral building block for the synthesis of β-amino alcohols and pharmaceutically relevant heterocycles. Its well-defined stereochemistry enables stereoselective transformations in medicinal chemistry workflows. The hydrochloride salt enhances bench stability and simplifies handling and purification, while maintaining compatibility with common coupling and functionalization reactions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   1.489
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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