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Structure of 888327-36-4
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2-Bromo-5-(trifluoromethoxy)pyridine features a trifluoromethoxy group that enhances electron-withdrawal and metabolic stability, while the bromine substituent enables efficient cross-coupling reactions. This pyridine scaffold integrates readily into pharmaceutical intermediates and functional materials under standard conditions.
2-Bromo-5-(trifluoromethoxy)pyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. The trifluoromethoxy group imparts enhanced metabolic stability and lipophilicity, while the bromine substituent provides high reactivity under standard coupling conditions. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H317
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: