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Structure of 88912-23-6
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2,6-Difluoroisonicotinic acid features a fluorinated pyridine core with strategically positioned electron-withdrawing substituents. This configuration enhances metabolic stability and modulates electronic properties for use in pharmaceutical intermediates and agrochemical scaffolds. The compound exhibits robust bench stability and facilitates efficient coupling reactions under standard conditions.
2,6-Difluoroisonicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated heterocycles and bioactive molecules. Its ortho-fluorine substituents enhance metabolic stability and modulate electronic properties, while the carboxylic acid group facilitates direct coupling reactions or derivatization. The compound exhibits good bench stability and compatibility with standard amide bond formation protocols, making it well-suited for parallel library synthesis and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: