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Structure of 889884-94-0
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7-Fluoronaphthalen-2-ol features a fluorine atom at the 7-position of naphthalene, strategically positioned to modulate electronic properties and enhance metabolic stability. The phenolic hydroxyl group enables direct functionalization or hydrogen bonding interactions in synthetic applications. This dual-functionalized scaffold integrates readily into complex molecular architectures requiring precise electronic tuning and controlled reactivity under standard conditions.
7-Fluoronaphthalen-2-ol serves as a versatile building block for the synthesis of functionalized naphthalene derivatives, enabling direct substitution at the C-2 position via nucleophilic aromatic substitution. Its fluorine atom enhances electrophilicity at the adjacent ring position, facilitating coupling reactions with amines and thiols under mild conditions. The phenolic hydroxyl group provides a handle for derivatization, including etherification and esterification, while maintaining stability during standard synthetic manipulations. This compound functions reliably in medicinal chemistry and materials science applications requiring ortho-substituted naphthalene scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: