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Structure of 799557-87-2
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2-Chloro-5-(trifluoromethyl)pyrazine is a bench-stable, electron-deficient heterocycle featuring a chlorine at the 2-position and a trifluoromethyl group at the 5-position. This combination enhances reactivity in cross-coupling processes while maintaining stability under standard conditions. The molecule integrates readily into complex scaffolds for medicinal chemistry and materials science applications.
2-Chloro-5-(trifluoromethyl)pyrazine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its reactive chloro group and electron-deficient pyrazine core. The trifluoromethyl substituent enhances metabolic stability and lipophilicity, making it valuable for constructing bioactive heterocycles. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient synthesis of pharmaceutical intermediates and functional materials.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H227-H301
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Precautionary Statements : P210-P264-P270-P280-P330-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: