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Structure of 89088-55-1
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5-Bromo-1-methyl-1H-pyrazol-3-amine features a brominated pyrazole core with a methylated nitrogen at the 1-position, delivering enhanced stability and solubility. This electron-deficient heterocycle integrates readily into cross-coupling reactions, serving as a key building block for bioactive molecules in medicinal chemistry and agrochemical development.
5-Bromo-1-methyl-1H-pyrazol-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The bromine and primary amine groups offer orthogonal reactivity for sequential derivatization, while the methyl-substituted pyrazole core provides enhanced metabolic stability and favorable physicochemical properties. Bench-stable and readily purified by standard chromatography, it functions as a key scaffold in the synthesis of bioactive heterocycles and targeted therapeutics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: