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Structure of 89284-38-8
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3,5-Dichloro-2-methylpyrazine is a chlorinated pyrazine derivative featuring two chlorine atoms at the 3 and 5 positions and a methyl group at the 2 position. This electron-deficient heterocycle serves as a key scaffold in medicinal chemistry for bioactive compound synthesis. Its steric and electronic profile enables selective coupling reactions under mild conditions. The molecule exhibits enhanced stability and solubility in organic solvents, facilitating integration into multi-step synthetic sequences.
3,5-Dichloro-2-methylpyrazine serves as a versatile heterocyclic building block in medicinal chemistry and agrochemical synthesis. Its electron-deficient pyrazine core enables reliable Suzuki-Miyaura and Buchwald-Hartwig couplings, while the methyl and dichloro substituents offer orthogonal reactivity for downstream functionalization. Bench-stable and readily purified by flash chromatography, it facilitates efficient access to complex nitrogen-rich scaffolds under standard reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: