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Structure of 89938-05-6
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This pyrimidine derivative features a sterically hindered isopropyl group at the 6-position, enhancing stability and solubility in organic media. The electron-withdrawing dichloro substituents at the 2- and 4-positions create a strongly electron-deficient heterocycle ideal for cross-coupling reactions. This compound serves as a key scaffold in medicinal chemistry for kinase inhibitor development and functionalized heterocycle synthesis under standard conditions.
2,4-Dichloro-6-(propan-2-yl)pyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its dual chloro substituents facilitate nucleophilic substitution reactions under mild conditions, while the isopropyl group enhances solubility and metabolic stability. This compound functions as a key intermediate in the synthesis of kinase inhibitors and other bioactive heterocycles, offering reliable bench stability and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: