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CS-W001157 4
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Ethyl 2-(2-chloropyridin-3-yl)-2-oxoacetate

  • CAS No. 902837-56-3

  • Cat. No. CS-W014267
  • Molecule weight213.62
  • Purity≥98%
  • MDL No.MFCD07781194

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-(2-chloropyridin-3-yl)-2-oxoacetate|CS-W014267

Structure of 902837-56-3

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General Information

  • CAS No. 902837-56-3
  • Cat. No. CS-W014267
  • Purity ≥98%
  • MDL No. MFCD07781194
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈ClNO₃
  • Molecular Weight 213.62
  • Synonym(s) ethyl-2-chloro-3-pyridylglyoxylate
  • SMILES CCOC(=O)C(=O)C1=CC=CN=C1Cl

Description

Azido-PEG3-Val-Cit-PAB-PNP is a cleavable peptide ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. PNP groupg is a good leaving group when treating with aminebearing payload. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   56.26
  • LogP   1.4808
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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