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Structure of 90725-50-1
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6-Bromo-3-methyl-2,3-dihydro-1H-indol-2-one features a brominated indolinone scaffold with enhanced reactivity at the C6 position. The methyl group at C3 provides steric and electronic modulation, while the dihydroindolone core offers stability under standard conditions. This compound serves as a key intermediate in the synthesis of bioactive heterocycles, particularly in medicinal chemistry applications involving palladium-catalyzed cross-coupling reactions.
6-Bromo-3-methyl-2,3-dihydro-1H-indol-2-one serves as a versatile building block for the synthesis of biologically active indole derivatives. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the keto group facilitates nucleophilic addition and condensation processes. The molecule exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: