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Structure of 158326-84-2
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6-Bromo-3,3-dimethyl-2,3-dihydro-1H-indol-2-one is a sterically hindered indolinone derivative featuring a bromine substituent at the C6 position and two methyl groups at C3. This configuration enhances stability and directs regioselective functionalization in synthetic transformations. The molecule serves as a key scaffold for medicinal chemistry campaigns targeting kinase inhibitors and bioactive heterocycles.
6-Bromo-3,3-dimethyl-2,3-dihydro-1H-indol-2-one serves as a versatile building block for the synthesis of substituted indolinones and related heterocyclic scaffolds. The bromine at the 6-position enables palladium-catalyzed cross-coupling reactions, while the sterically hindered 3,3-dimethyl substitution enhances bench stability and facilitates purification. This compound functions effectively in late-stage functionalization strategies and supports diverse transformations under standard reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: