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Structure of 90778-25-9
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3-Amino-5-(trifluoromethyl)pyridin-2(1H)-one features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the amino substituent provides a reactive handle for derivatization. This scaffold integrates readily into bioactive molecules, offering improved solubility and target affinity in medicinal chemistry applications.
3-Amino-5-(trifluoromethyl)pyridin-2(1H)-one serves as a versatile building block in medicinal chemistry, enabling efficient construction of bioactive heterocycles. The amino group facilitates nucleophilic substitution and coupling reactions, while the trifluoromethyl moiety enhances metabolic stability and lipophilicity. Its pyridinone core provides hydrogen-bonding capability and structural rigidity, supporting interactions with biological targets. Bench-stable and readily purified, it functions effectively in standard synthetic workflows for API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: