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N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-methyl-L-glutamine

  • CAS No. 910056-51-8

  • Cat. No. CS-0166905
  • Purity≥97%
  • MDL No.MFCD30475988
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-methyl-L-glutamine|CS-0166905

Structure of 910056-51-8

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Description

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-methyl-L-glutamine is a protected glutamine derivative featuring a fluorenylmethoxycarbonyl (Fmoc) group at the Nα position and a methyl substituent on the side-chain amide. This configuration enables selective incorporation in peptide synthesis, combining enhanced stability with efficient deprotection under mild basic conditions. The Fmoc handle facilitates orthogonal protection strategies in solid-phase workflows.

Application

N₂-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N²-methyl-L-glutamine serves as a protected amino acid building block for peptide synthesis, offering enhanced solubility and stability during coupling reactions. The Fmoc group enables orthogonal deprotection under mild basic conditions, while the N²-methyl substitution reduces racemization risk. This derivative facilitates efficient incorporation of glutamine side chains into complex peptides with high fidelity and ease of purification.

General Information

  • CAS No. 910056-51-8
  • Cat. No. CS-0166905
  • Purity ≥97%
  • MDL No. MFCD30475988
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₂N₂O₅
  • Molecular Weight 382.41
  • Synonym(s) FMOC-N-METHYL-L-GLUTAMINE
  • SMILES O=C(N)CC[C@@H](C(O)=O)N(C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C

Computational Chemistry Data

  • TPSA   109.93
  • LogP   2.586
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   7

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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