(R)-6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride

Name: (R)-6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 911372-77-5
Cat. No. CS-0042125
Purity≥97%
MDL No.MFCD22392661

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FedEx Limited Quantities Ground	$0.00
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(R)-6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride|CS-0042125

Structure of 911372-77-5

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Description

(R)-6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride is a chiral amine scaffold featuring a bench-stable, moisture-tolerant tetrahydro-naphthalene core. The para-methoxy substitution enhances electron density at the aromatic ring, while the protonated amine enables efficient salt formation for improved solubility and handling in synthetic workflows. This configuration supports stereoselective synthesis of bioactive molecules.

Application

(R)-6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride serves as a chiral building block for bioactive molecule synthesis, offering high diastereoselectivity in amine-directed transformations. The tetralin core provides rigidity and lipophilicity beneficial for medicinal chemistry applications. Bench-stable and readily purified via recrystallization, the hydrochloride salt enhances solubility and handling in standard organic protocols. Functions effectively in reductive amination, coupling reactions, and heterocycle formation.

General Information

CAS No. 911372-77-5
Cat. No. CS-0042125
Purity ≥97%
MDL No. MFCD22392661
Storage RT, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₆ClNO
Molecular Weight 213.70
Synonym(s) None
SMILES N[C@@H]1CCCC2=C1C=CC(OC)=C2.[H]Cl

Computational Chemistry Data

TPSA 35.25
LogP 2.4531
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride

CAS No. 911372-77-5

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