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Structure of 91420-25-6
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5-Bromo-2-methylpyridin-3-ol features a bromine substituent at the 5-position and a methyl group at the 2-position, flanking a phenolic hydroxyl on a pyridine core. This electron-deficient heterocycle integrates readily into cross-coupling reactions, offering enhanced stability under standard conditions. The hydroxyl group enables direct functionalization or metal coordination, streamlining access to complex scaffolds in medicinal chemistry and materials science.
5-Bromo-2-methylpyridin-3-ol serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromine substituent. The phenolic hydroxyl group offers orthogonal reactivity for derivatization, while the methyl and pyridine functionalities provide stability and compatibility with standard synthetic workflows. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthesis of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: